Top 10 Best b 6 vitamins in 2026

Last Updated - 6/7/2026

🏆Best Choice

Nature's Bounty

Nature's Bounty Vitamin B6 100mg Tablets - Supports Energy Metabolism & Nervous System Health, 100 Ct

9.8

ChoiceComparer.com Score

9.8

/ 10

Outstanding

Main highlights

•FOR CELLULAR ENERGY SUPPORT (1): Nature's Bounty Vitamin B-6 helps convert food into energy; maintaining cellular energy levels and supporting overall energy metabolism (1)
•CARDIOVASCULAR AND NERVOUS SYSTEM SUPPORT (1): As a key element in the B-Complex group; this B6 supplement supports cardiovascular and nervous system health (1)
•MAINTAINS HEALTHY HOMOCYSTEINE LEVELS (1): Our B-6 Vitamins contribute to maintaining healthy homocysteine levels already within a normal range (1)
•SUITABLE FOR VEGETARIANS: Our non-GMO; gluten and sugar-free B6 Vitamins 100mg tablets are free from artificial flavors; well-suited for vegetarian diets
•TRUSTED QUALITY AND CONSISTENCY: With nearly 50 years in quality vitamins and supplements; Nature's Bounty provides Vitamin B-6 tablets backed by scientific research

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$4.83

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Nature Made

Nature Made Vitamin B6 100 mg Tablets, 100 Count for Metabolic Health

9.7

ChoiceComparer.com Score

9.7

/ 10

Outstanding

Main highlights

•Contains a 100-day supply of Nature Made Vitamin B6 100 mg Tablets, 100 tablets per bottle.
•Essential for carbohydrate, protein and amino acid metabolism
•Adults, take 1 tablet daily with water and a meal.
•Guaranteed to meet our high quality standards. Made from carefully selected ingredients under strict manufacturing processes. No color added, no artificial flavors, no preservatives, gluten free.
•USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. Visit the USP verified website for more information.
•These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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$8.99

$10.59

-15%

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Solgar

Solgar Vitamin B6 25 mg, 100 Tablets - Supports Energy Metabolism, Heart Health & Healthy Nervous System - B Complex Supplement - Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings

9.5

ChoiceComparer.com Score

9.5

/ 10

Outstanding

Main highlights

•B Complex Supplement; Vitamin B6 is part of the group of essential nutrients known as the B Complex; This formulation provides 25mg of vitamin B6 per serving
•Energy Metabolism; B Complex vitamins, including B6, work to support energy metabolism in the body; B6 helps maintain a healthy nervous system
•Heart Health; Along with folic acid and B12, B6 promotes heart health by supporting healthy levels of homocysteine already in a normal range; It also plays an integral role in the production of red blood cells
•Gluten, Wheat & Dairy Free; Solgar Vitamin B6 is suitable for vegans and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color; Suitable for vegetarians
•The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials

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$6.02

$8.49

-29%

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Nutricost

Nutricost Vitamin B6 (Pyridoxine HCl) 100mg, 240 Capsules

9.4

ChoiceComparer.com Score

9.4

/ 10

Excellent

Main highlights

•100mg of Vitamin B6 (Pyridoxine HCl) per Capsule
•240 Vitamin B6 Capsules In Each Bottle
•1 Serving, Just 1 Capsule
•Non-GMO, Gluten Free, 3rd Party Tested
•Made in a GMP Compliant, FDA Registered Facility

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$11.95

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THORNE

THORNE - B-Complex #6 - Vitamin B Complex with Active Forms of Essential B Vitamins & Extra B6-60 Servings

9.2

ChoiceComparer.com Score

9.2

/ 10

Excellent

Main highlights

•Complete Formula: Each capsule provides a balance of 8 water-soluble B vitamins (B1, B2, B3, B5, B6, B7, B9, and B12) plus choline in their active, tissue-ready forms to enhance bioavailability in the body
•Nerves and Brain: Formulated with extra vitamin B6 to support neurological function and support a balanced mood for athletes looking to optimize their pre-competition mindset*
•Muscle Support: Promotes creatine conversion, supports the metabolism of amino acids and protein, and reduces exercise-related spasms and cramps by increasing the bioavailability of magnesium*
•NSF Certified for Sport: Tested for compliance with label claims and to ensure the absence of nearly 300 substances banned by many major athletic organizations
•Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

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$24.60

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NOW Foods

NOW Foods Supplements, Vitamin B-6 (Pyridoxine HCl) 100 mg, Cardiovascular Health, 250 Veg Capsules

9.1

ChoiceComparer.com Score

9.1

/ 10

Excellent

Main highlights

•SUPPORTS HEALTHY HOMOCYSTEINE METABOLISM*: B-6 plays an important role in regulating homocysteine metabolism in the body.* Homocysteine, a by-product of the methionine cycle, is known to be destructive to bodily tissues, especially vascular structures
•IMPORTANT FOR NERVOUS SYSTEM FUNCTION*: Vitamin B-6 is a cofactor in numerous enzymatic reactions and is required for the metabolism of fats, carbohydrates, and proteins*
•CERTIFICATIONS/CLASSIFICATIONS: Halal, Kosher Contains Gelatin, Non-GMO, Soy Free
•GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
•Packaged in the USA by a family owned and operated company since 1968

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$11.60

$19.99

-42%

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Bronson

Bronson Vitamin B6 100mg Premium Vitamin B6 Supplement, 250 Tablets

8.9

ChoiceComparer.com Score

8.9

/ 10

Great

Main highlights

•Metabolism & Immune Function: Vitamin B6 promotes protein metabolism, and immune function.
•Superior Quality: Laboratory tested, manufactured at cGMP registered facility.
•Trusted Since 1960: The pioneers of Bronson Vitamins were a group of pharmacists who witnessed the benefits of vitamins and mineral supplementation firsthand with their patients. Bronson Vitamins have been consistently mentioned by top medical professionals since our inception in 1960.

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$9.97

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Life Extension

Life Extension Vitamin B6, 250 mg, high Potency, Cardiovascular Health, neurological Health, Eye Health, Healthy Kidney Function, Gluten-Free, Non-GMO, Vegetarian, 100 Capsules

8.8

ChoiceComparer.com Score

8.8

/ 10

Great

Main highlights

•Whole-body health – Vitamin B6 helps inhibit glycation reactions. This, in turn, can support a healthy nervous system, cardiovascular health, eye health and even kidney function.
•The feel-good vitamin – Vitamin B6 is an important part of biological processes like cellular energy production, immune response and serotonin production (the “feel-good” neurotransmitter).
•High-potency B6 – Your body doesn’t produce vitamin B6, so you have to get it from a healthy diet or a high-potency vitamin B6 supplement like this one: 250 mg in each healthy dose.
•Ingredients matter – We use the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one. 
•Live your healthiest life – We believe the answers to a healthier life are in reach, and that scientific research is the key to getting there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.

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$9.75

$13.00

-25%

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KAL

KAL Vitamin B-6, B-12 & Folic Acid Supplement, Heart Health, Energy & Red Blood Cell Support*, with Vitamin B12 Methylcobalamin & Folate, Natural Berry Flavor, 60 Servings, 60 ActivMelt Micro Tablets

8.6

ChoiceComparer.com Score

8.6

/ 10

Good

Main highlights

•Superior B Vitamins: Formulated for high absorption, each fast-dissolving micro tablet provides 3 mg Vitamin B-6, 1000 mcg B12 Methylcobalamin and 680 mcg DFE Folate (400 mcg Folic Acid).
•Strong Synergy: Powerful Vitamin B blend is formulated to help support healthy energy levels & metabolism, red blood cell synthesis and normal homocysteine levels in the blood for a healthy heart.*
•Preferred Form: This superior formula contains vitamins B6 and B12 in their biologically active, coenzyme forms, P-5-P and Methyl B12.
•Bioavailable Support: Trademarked ActivMelt micro tablets melt instantly in the mouth and release the nutrients quickly for maximum absorption and efficacy in the body. Plus you’ll love the natural berry flavor!
•KAL Quality: Our B6, B12 & Folic Acid is vegetarian, and like all KAL supplements, is lab verified for the purity and potency of its ingredients and comes with our standard 60-day money back guarantee.

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$12.55

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NOW Foods

Now Foods B-6 100mg 100 Capsules

8.5

ChoiceComparer.com Score

8.5

/ 10

Good

Main highlights

•B-6 100mg 100 caps by now foods
•NOWSUPPVitamin-Vitamins- 100CAPS
•Now foods product upc: 733739004567

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$7.51

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